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The drug Cialis is made in the dosage form of tablets for oral administration, film-coated.

They have a yellow color, a round shape and a biconvex surface. The main active ingredient of the drug is tadalafil, its content in one tablet is 5 and 20 mg. It also contains excipients, to whichth include: Magnesium stearate. Lactose monohydrate. Sodium lauryl sulfate. Hyprolosis. Titanium dioxide. Croscarmellose sodium. Triacetin. Iron oxide is yellow. Hypromellose. Cialis tablets are packaged in an aluminum foil blister of 1, 2, 4, 8 or 14 pieces. The cardboard box contains 1 or 2 blisters with tablets, as well as instructions for the use of the drug.

The main active ingredient of Cialis tablets tadalafil improves the erectile function of the penis, increasing blood flow to the corpus cavernosum. This is due to the suppression of the enzyme phosphodiesterase 5, which in turn leads to the accumulation of nitric oxide in the corpus cavernosum. Nitric oxide stimulates the accumulation of cyclic guanine triphosphate (cGMP), which reduces the tone of the walls of the vascular bed, expands their lumen, and also expands arterial vessels, helping to increase blood flow to the cavernous bodies of the penis with improved erection.

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After taking the Cialis tablet inside, the active ingredient tadalafil is quickly and almost completely absorbed into the blood from the lumen of the small intestine.

It reaches its maximum concentration in the blood after 2 hours. Tadalafil is evenly distributed in the tissues, enters the corpus cavernosum, where it has a therapeutic effect. It is metabolized in the liver with the formation of inactive decay products, which are excreted from the body mainly in the feces and, to a lesser extent, in the urine. The therapeutic effect after taking the Cialis tablet develops within 15-20 minutes and can persist for a period of time up to 36 hours.

The main medical indication for taking Cialis tablets is to improve the erectile function of the penis in men, the violation of which was provoked by various reasons. Taking Cialis tablets is contraindicated in case of increased sensitivity of the patient's body to any of the components of the drug, in children under 18 years of age, as well as in the joint administration of drugs of pharmacological groups containing organic nitrates.

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